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Location:  Home > Details for node Tetrahydrofolate
Type: Compound GRN ID: nc50101 Name: Tetrahydrofolate
Annotation: Tetrahydrofolate; 5,6,7,8-Tetrahydrofolate; Tetrahydrofolic acid; THF; (6S)-Tetrahydrofolate; (6S)-Tetrahydrofolic acid; (6S)-THFA
KEGG Acc.: C00101
CHEBI ID:
Formula: C19H23N7O6
M.W.: 445.4292
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 Protein modification
 Protein-protein interaction
        also include predicted relationship
 Compound-protein interaction
 TF-target gene regulation
 Small RNA-target regulation
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 Carrier and transported molecule
 Catalytic chemical reaction
 Co-expressed gene pair
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Relationship type:  protein modification     catalytic chemical reaction     protein-protein interaction    
compound-protein interaction     TF-target gene regulation     small RNA-target regulation    
co-expressed gene pair     carrier and transported molecule     family/complex and member
Relationship evidence:  Solid line: validated          Dashed line: predicted
Relationship direction: Arrow: positive          T shape: negative          None arrow: unknown or n/a
Hormone association: Thicker line: hormone related relationship         : hormone related Node
Node type:  Transcription factor or transcriptional regulator       Compound       Kinase
 Small regulatory RNA (miRNA & ta-siRNA)       Other nodes
No. Path
2 Tetrahydrofolate  --  has product (in catalytic reaction)  --  10-Formyltetrahydrofolate
3 Tetrahydrofolate  --  has product (in catalytic reaction)  --  5,10-Methylenetetrahydrofolate
4 Tetrahydrofolate  --  has product (in catalytic reaction)  --  Dihydrofolate
5 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AT5G47435
6 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AT4G17360
7 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  PANB2
8 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  3-Methyl-2-oxobutanoic acid
9 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  KPHMT1; PANB1
10 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  pde194
11 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AT2G35040
12 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
13 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AT1G31220
14 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  5'-Phosphoribosylglycinamide
15 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM2
16 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM
17 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3
18 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM4
19 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  EDA36; EDA37; SHM5
20 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM7
21 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM6
22 Tetrahydrofolate  --  has product (in catalytic reaction)  --  10-Formyltetrahydrofolate  --  has product (in catalytic reaction)  --  Formate
23 Tetrahydrofolate  --  has product (in catalytic reaction)  --  10-Formyltetrahydrofolate  --  has product (in catalytic reaction)  --  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
24 Tetrahydrofolate  --  has product (in catalytic reaction)  --  10-Formyltetrahydrofolate  --  has product (in catalytic reaction)  --  5'-Phosphoribosyl-N-formylglycinamide
25 Tetrahydrofolate  --  has product (in catalytic reaction)  --  10-Formyltetrahydrofolate  --  is product (in catalytic reaction) of  --  THFS
26 Tetrahydrofolate  --  has product (in catalytic reaction)  --  5,10-Methylenetetrahydrofolate  --  has product (in catalytic reaction)  --  2-Dehydropantoate
27 Tetrahydrofolate  --  has product (in catalytic reaction)  --  5,10-Methylenetetrahydrofolate  --  has product (in catalytic reaction)  --  dTMP
28 Tetrahydrofolate  --  has product (in catalytic reaction)  --  5,10-Methylenetetrahydrofolate  --  is product (in catalytic reaction) of  --  AT1G11860
29 Tetrahydrofolate  --  has product (in catalytic reaction)  --  5,10-Methylenetetrahydrofolate  --  is product (in catalytic reaction) of  --  S-Aminomethyldihydrolipoylprotein
30 Tetrahydrofolate  --  has product (in catalytic reaction)  --  5,10-Methylenetetrahydrofolate  --  is product (in catalytic reaction) of  --  MTHFR1
31 Tetrahydrofolate  --  has product (in catalytic reaction)  --  5,10-Methylenetetrahydrofolate  --  is product (in catalytic reaction) of  --  5-Methyltetrahydrofolate
32 Tetrahydrofolate  --  has product (in catalytic reaction)  --  5,10-Methylenetetrahydrofolate  --  is product (in catalytic reaction) of  --  MTHFR2
33 Tetrahydrofolate  --  has product (in catalytic reaction)  --  Dihydrofolate  --  is product (in catalytic reaction) of  --  THY-2
34 Tetrahydrofolate  --  has product (in catalytic reaction)  --  Dihydrofolate  --  is product (in catalytic reaction) of  --  dUMP
35 Tetrahydrofolate  --  has product (in catalytic reaction)  --  Dihydrofolate  --  is product (in catalytic reaction) of  --  THY-1
36 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AT5G47435  --  interacts with  --  ATPRR1; PRR1
37 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AT4G17360  --  has similar expression pattern (mutual information value=0.908457) with  --  AT3G17930
38 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AT4G17360  --  has similar expression pattern (mutual information value=0.814613) with  --  AT4G10000
39 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  PANB2  --  interacts with  --  ATGRX4; GRX4
40 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  3-Methyl-2-oxobutanoic acid  --  has product (in catalytic reaction)  --  alpha-Isopropylmalate
41 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  3-Methyl-2-oxobutanoic acid  --  has product (in catalytic reaction)  --  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
42 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  3-Methyl-2-oxobutanoic acid  --  is product (in catalytic reaction) of  --  AT3G23940
43 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  3-Methyl-2-oxobutanoic acid  --  is product (in catalytic reaction) of  --  2,3-Dihydroxy-3-methylbutanoate
44 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AT2G35040  --  has similar expression pattern (mutual information value=0.825007) with  --  PYRB
45 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AT2G35040  --  has similar expression pattern (mutual information value=0.837186) with  --  ATPURM; EMB2818; PUR5
46 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide  --  is product (in catalytic reaction) of  --  AT4G18440
47 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide  --  is product (in catalytic reaction) of  --  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
48 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide  --  is product (in catalytic reaction) of  --  N6-(1,2-Dicarboxyethyl)-AMP
49 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide  --  is product (in catalytic reaction) of  --  AT1G36280
50 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  5'-Phosphoribosylglycinamide  --  is product (in catalytic reaction) of  --  AT1G09830
51 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  5'-Phosphoribosylglycinamide  --  is product (in catalytic reaction) of  --  5-Phosphoribosylamine
52 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  interacts with  --  UBP16
53 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.26297) with  --  PSBW
54 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.32419) with  --  EDA3
55 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.5285) with  --  AT2G27680
56 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=0.802438) with  --  AT2G19650
57 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.19799) with  --  AOR
58 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.51869) with  --  ZKT
59 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.03511) with  --  AT1G65490
60 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.39536) with  --  TLP18.3
61 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.42627) with  --  CRB; CSP41B; HIP1.3
62 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.37727) with  --  LQY1
63 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.31687) with  --  OE23; OEE2; PSBP-1; PSII-P
64 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.06955) with  --  FTSH1
65 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.376) with  --  NDF1; NDH48
66 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.26378) with  --  ATCDSP32; CDSP32
67 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.20036) with  --  CLPP5; NCLPP1; NCLPP5
68 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=0.839916) with  --  mtLPD1
69 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.32527) with  --  AT1G76450
70 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.5342) with  --  ATCYP38; CYP38
71 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.45329) with  --  PGK1
72 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=0.949806) with  --  AtFAD7; FAD7; FADD
73 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=0.949806) with  --  AtFAD8; FAD8
74 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.70136) with  --  AT1G18060
75 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.22055) with  --  HCF173
76 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.25973) with  --  PSAD-1
77 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.36801) with  --  PETC; PGR1
78 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.38309) with  --  ATPC1
79 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.44905) with  --  PGR5-LIKE A
80 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.27928) with  --  FAD6; FADC; SFD4
81 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.22588) with  --  AtGLDP1; GLDP1
82 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.33878) with  --  AT4G35250
83 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.56193) with  --  FBA2
84 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.01949) with  --  ACA1; ATACA1; CAH1
85 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.0775) with  --  ATGR2; EMB2360; GR
86 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.47869) with  --  SBPASE
87 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.29611) with  --  AT3G61870
88 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.42563) with  --  AT5G08650
89 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.32348) with  --  HCF136
90 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.40616) with  --  FTSH5; VAR1
91 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.34045) with  --  CLB4; CSB3; GCPE; HDS; ISPG
92 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.26627) with  --  ATLDA; ATPU1; LDA; PU1
93 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.41119) with  --  FD-GOGAT; GLS1; GLU1; GLUS
94 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM1; SHMT1; STM  --  has similar expression pattern (mutual information value=1.24383) with  --  RCA
95 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  interacts with  --  AT4G08520
96 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.929483) with  --  EMB3108
97 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.839203) with  --  AtHsp90.5; CR88; EMB1956; Hsp88.1; HSP90.5
98 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.924584) with  --  AT1G48460
99 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.871807) with  --  FLN2
100 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.871024) with  --  GYRB1
101 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.871024) with  --  GYRB2
102 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.837925) with  --  GYRA
103 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=1.00726) with  --  emb2742
104 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.939766) with  --  AT3G57940
105 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.849713) with  --  AT5G10920
106 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  AtSHMT3; SHM3  --  has similar expression pattern (mutual information value=0.858151) with  --  ATOEP80; EMB213; OEP80; TOC75-V
107 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM4  --  interacts with  --  AT4G37130
108 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM4  --  has similar expression pattern (mutual information value=1.00251) with  --  MAT3
109 Tetrahydrofolate  --  is product (in catalytic reaction) of  --  SHM4  --  has similar expression pattern (mutual information value=0.829519) with  --  NRS/ER; UER1
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