MET-COFEA:
A Novel Liquid Chromatography-Mass Spectrometry Data Processing Platform for Metabolite Compound Feature Extraction and Annotationn
 
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  • MET-COFEA Software (Beta version - last updated: 10/15/2013, for Windows 32-bit and 64-bit). Unzip the file onto a local drive, then click MET_COFEA.exe to run the program.
  • Gamma version 32bit - updated: 01/12/2016, for Windows 32-bit to be compatible with specific CDF files that are intermediately from the customized MS converting tools and recording blank for some redundant information vectors.
  • In order to suit .mzdata.xml data to MET-COFEA, script_mzdata2cdf can help you realize the MS data format converting.
  • Gamma version 64bit - updated: 01/12/2016, for Windows 64-bit only to be furtherly compatible with special case with very large CDF files(single .CDF >1GB). To run this 64 bit MET-COFEA, 0xc000007b Application Error maybe be met and needed to be fixed at first.
  • User Manual (Beta version)
  • Test Sample Data (~296MB)
  • Dataset Presented in our paper: Standard Mixture
  • File nameDescriptionDownload Link
    POS_STANDMIX-50NMConcentration: Normal, Ionization: (+)ESI Download
    POS_STANDMIX-5NMConcentration: 1:10 Dilution, Ionization: (+)ESI Download
    NEG_STANDMIX-50NMConcentration: Normal, Ionization: (-)ESI Download
    NEG_STANDMIX-5NMConcentration: 1:10 Dilution, Ionization: (-)ESI Download
  • Dataset Presented in our paper: Medicago Leaf
  • File nameDescriptionDownload Link
    A17_A1_LEAFPlace: Australia, Tissue: Leaf, Allocated Ecotype: A17_A, Ionization: (-)ESI Download
    A17_A2_LEAFPlace: Australia, Tissue: Leaf, Allocated Ecotype: A17_A, Ionization: (-)ESI Download
    A17_A3_LEAFPlace: Australia, Tissue: Leaf, Allocated Ecotype: A17_A, Ionization: (-)ESI Download
    DZA242_A1_LEAFPlace: Algeria, Tissue: Leaf, Allocated Ecotype: DZA242_A, Ionization: (-)ESI Download
    DZA242_A2_LEAFPlace: Algeria, Tissue: Leaf, Allocated Ecotype: DZA242_A, Ionization: (-)ESI Download
    DZA242_A3_LEAFPlace: Algeria, Tissue: Leaf, Allocated Ecotype: DZA242_A, Ionization: (-)ESI Download
    ESP104_A1_LEAFPlace: Spain, Tissue: Leaf, Allocated Ecotype: ESP104_A, Ionization: (-)ESI Download
    ESP104_A2_LEAFPlace: Spain, Tissue: Leaf, Allocated Ecotype: ESP104_A, Ionization: (-)ESI Download
    ESP104_A3_LEAFPlace: Spain, Tissue: Leaf, Allocated Ecotype: ESP104_A, Ionization: (-)ESI Download
    ESP105_A1_LEAFPlace: Spain, Tissue: Leaf, Allocated Ecotype: ESP105_A, Ionization: (-)ESI Download
    ESP105_A2_LEAFPlace: Spain, Tissue: Leaf, Allocated Ecotype: ESP105_A, Ionization: (-)ESI Download
    ESP105_A3_LEAFPlace: Spain, Tissue: Leaf, Allocated Ecotype: ESP105_A, Ionization: (-)ESI Download
  • Dataset Presented in our paper: Medicago Root
  • File nameDescriptionDownload Link
    A17_T1_ROOTPlace: Australia, Tissue: Root, Allocated Ecotype: A17_T, Ionization: (-)ESI Download
    A17_T2_ROOTPlace: Australia, Tissue: Root, Allocated Ecotype: A17_T, Ionization: (-)ESI Download
    A17_T3_ROOTPlace: Australia, Tissue: Root, Allocated Ecotype: A17_T, Ionization: (-)ESI Download
    ESP104_T1_ROOTPlace: Spain, Tissue: Root, Allocated Ecotype: ESP104_T, Ionization: (-)ESI Download
    ESP104_T2_ROOTPlace: Spain, Tissue: Root, Allocated Ecotype: ESP104_T, Ionization: (-)ESI Download
    ESP104_T3_ROOTPlace: Spain, Tissue: Root, Allocated Ecotype: ESP104_T, Ionization: (-)ESI Download
    ESP104_A1_ROOTPlace: Spain, Tissue: Root, Allocated Ecotype: ESP104_A, Ionization: (-)ESI Download
    ESP104_A2_ROOTPlace: Spain, Tissue: Root, Allocated Ecotype: ESP104_A, Ionization: (-)ESI Download
    ESP104_A3_ROOTPlace: Spain, Tissue: Root, Allocated Ecotype: ESP104_A, Ionization: (-)ESI Download
    ESP105_A1_ROOTPlace: Spain, Tissue: Root, Allocated Ecotype: ESP105_A, Ionization: (-)ESI Download
    ESP105_A2_ROOTPlace: Spain, Tissue: Root, Allocated Ecotype: ESP105_A, Ionization: (-)ESI Download
    ESP105_A3_ROOTPlace: Spain, Tissue: Root, Allocated Ecotype: ESP105_A, Ionization: (-)ESI Download