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A Graph Search-Empowered Integrative Database of Arabidopsis Signaling Transduction, Metabolism and Gene Regulation Networks   
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Relationship Details
Type: protein-protein interaction GRN ID: re144923 Name: Validated: Y
Direction: Unknown or N/A
Steps: Direct effect
Upstream node(s):
Downstream node(s):
Pathways: Gibberellins
References:
  • Saijo Y, Sullivan JA, Wang H, Yang J, Shen Y, Rubio V, Ma L, Hoecker U, Deng XW. The COP1-SPA1 interaction defines a critical step in phytochrome A-mediated regulation of HY5 activity. Genes Dev. 2003 Nov 1;17(21):2642-7. PubMed PMID: 14597662; PubMed Central PMCID: PMC280614.
  • Holm M, Hardtke CS, Gaudet R, Deng XW. Identification of a structural motif that confers specific interaction with the WD40 repeat domain of Arabidopsis COP1. EMBO J. 2001 Jan 15;20(1-2):118-27. PubMed PMID: 11226162; PubMed Central PMCID: PMC140188.
  • Singh A, Ram H, Abbas N, Chattopadhyay S. Molecular interactions of GBF1 with HY5 and HYH proteins during light-mediated seedling development in Arabidopsis thaliana. J Biol Chem. 2012 Jul 27;287(31):25995-6009. doi: 10.1074/jbc.M111.333906. Epub 2012 Jun 12. PubMed PMID: 22692212; PubMed Central PMCID: PMC3406683.
  • Maier A, Schrader A, Kokkelink L, Falke C, Welter B, Iniesto E, Rubio V, Uhrig JF, Hülskamp M, Hoecker U. Light and the E3 ubiquitin ligase COP1/SPA control the protein stability of the MYB transcription factors PAP1 and PAP2 involved in anthocyanin accumulation in Arabidopsis. Plant J. 2013 May;74(4):638-51. doi: 10.1111/tpj.12153. Epub 2013 Mar 25. PubMed PMID: 23425305.
  • Abbas N, Maurya JP, Senapati D, Gangappa SN, Chattopadhyay S. Arabidopsis CAM7 and HY5 physically interact and directly bind to the HY5 promoter to regulate its expression and thereby promote photomorphogenesis. Plant Cell. 2014 Mar;26(3):1036-52. doi: 10.1105/tpc.113.122515. Epub 2014 Mar 7. PubMed PMID: 24610722; PubMed Central PMCID: PMC4001367.
  • Lau OS, Deng XW. Plant hormone signaling lightens up: integrators of light and hormones. Curr Opin Plant Biol. 2010 Oct;13(5):571-7. doi: 10.1016/j.pbi.2010.07.001. Epub 2010 Aug 23. Review. PubMed PMID: 20739215.
 
Cross Reference: biogrid:268623  biogrid:334681  biogrid:664467  biogrid:823490  biogrid:1257357  
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