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A Graph Search-Empowered Integrative Database of Arabidopsis Signaling Transduction, Metabolism and Gene Regulation Networks   
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Relationship Details
Type: protein-protein interaction GRN ID: re157886 Name: Validated: Y
Direction: Unknown or N/A
Steps: Direct effect
Upstream node(s):
Downstream node(s):
References:
  • Favory JJ, Stec A, Gruber H, Rizzini L, Oravecz A, Funk M, Albert A, Cloix C, Jenkins GI, Oakeley EJ, Seidlitz HK, Nagy F, Ulm R. Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis. EMBO J. 2009 Mar 4;28(5):591-601. doi: 10.1038/emboj.2009.4. Epub 2009 Jan 22. PubMed PMID: 19165148; PubMed Central PMCID: PMC2657586.
  • Cloix C, Kaiserli E, Heilmann M, Baxter KJ, Brown BA, O'Hara A, Smith BO, Christie JM, Jenkins GI. C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16366-70. doi: 10.1073/pnas.1210898109. Epub 2012 Sep 17. PubMed PMID: 22988111; PubMed Central PMCID: PMC3479605.
  • Crefcoeur RP, Yin R, Ulm R, Halazonetis TD. Ultraviolet-B-mediated induction of protein-protein interactions in mammalian cells. Nat Commun. 2013;4:1779. doi: 10.1038/ncomms2800. PubMed PMID: 23653191.
  • Heijde M, Binkert M, Yin R, Ares-Orpel F, Rizzini L, Van De Slijke E, Persiau G, Nolf J, Gevaert K, De Jaeger G, Ulm R. Constitutively active UVR8 photoreceptor variant in Arabidopsis. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20326-31. doi: 10.1073/pnas.1314336110. Epub 2013 Nov 25. PubMed PMID: 24277841; PubMed Central PMCID: PMC3864333.
  • Huang X, Yang P, Ouyang X, Chen L, Deng XW. Photoactivated UVR8-COP1 module determines photomorphogenic UV-B signaling output in Arabidopsis. PLoS Genet. 2014 Mar 20;10(3):e1004218. doi: 10.1371/journal.pgen.1004218. eCollection 2014 Mar. PubMed PMID: 24651064; PubMed Central PMCID: PMC3961177.
  • Yin R, Arongaus AB, Binkert M, Ulm R. Two distinct domains of the UVR8 photoreceptor interact with COP1 to initiate UV-B signaling in Arabidopsis. Plant Cell. 2015 Jan;27(1):202-13. doi: 10.1105/tpc.114.133868. Epub 2015 Jan 27. PubMed PMID: 25627067; PubMed Central PMCID: PMC4330580.
 
Cross Reference: biogrid:692116  biogrid:728048  biogrid:869124  biogrid:918242  biogrid:1105141  biogrid:1239064  
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