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A Graph Search-Empowered Integrative Database of Arabidopsis Signaling Transduction, Metabolism and Gene Regulation Networks   
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Relationship Details
Type: TF-target gene regulation GRN ID: re144466 Name: Validated: Y
Annotation:  FLC regulates the expression of SOC1 by recognizing its binding site
Direction: Positive
Steps: Direct effect
Upstream node(s):
Downstream node(s):
Pathways: Gibberellins
References:
  • Hepworth SR, Valverde F, Ravenscroft D, Mouradov A, Coupland G. Antagonistic regulation of flowering-time gene SOC1 by CONSTANS and FLC via separate promoter motifs. EMBO J. 2002 Aug 15;21(16):4327-37. PubMed PMID: 12169635; PubMed Central PMCID: PMC126170.
  • Seo E, Lee H, Jeon J, Park H, Kim J, Noh YS, Lee I. Crosstalk between cold response and flowering in Arabidopsis is mediated through the flowering-time gene SOC1 and its upstream negative regulator FLC. Plant Cell. 2009 Oct;21(10):3185-97. doi: 10.1105/tpc.108.063883. Epub 2009 Oct 13. PubMed PMID: 19825833; PubMed Central PMCID: PMC2782271.
 
Cross Reference: TRANSFAC:R19512  
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