Welcome to HRGRN: A Graph Search-Empowered Integrative Database of Arabidopsis Signaling Transduction, Metabolism and Gene Regulation Networks

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	Welcome to HRGRN A Graph Search-Empowered Integrative Database of Arabidopsis Signaling Transduction, Metabolism and Gene Regulation Networks

Location: Home > Details for node AHK3

Type: Protein	GRN ID: np04040	Name: AHK3
Annotation:	AHK3, HK3 \| histidine kinase 3 [EC:2.7.13.3]
Gene Locus:	AT1G27320
Transcription factor / transcriptional regulator:	response regulator and putative novel transcription factor family RR-A-type
References:	Higuchi M, Pischke MS, Mähönen AP, Miyawaki K, Hashimoto Y, Seki M, Kobayashi M, Shinozaki K, Kato T, Tabata S, Helariutta Y, Sussman MR, Kakimoto T. In planta functions of the Arabidopsis cytokinin receptor family. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8821-6. Epub 2004 May 27. PubMed PMID: 15166290; PubMed Central PMCID: PMC423279. Riefler M, Novak O, Strnad M, Schmülling T. Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism. Plant Cell. 2006 Jan;18(1):40-54. Epub 2005 Dec 16. PubMed PMID: 16361392; PubMed Central PMCID: PMC1323483.
Pathways:	Cytokinins
Gene Expression (Affy ATH1 probeset):	264448_at

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Protein modification

Protein-protein interaction
also include predicted relationship

Compound-protein interaction

TF-target gene regulation

Small RNA-target regulation
also include predicted relationship

Carrier and transported molecule

Catalytic chemical reaction

Co-expressed gene pair
with mutual information value >

Ignore nodes having > relationships

Relationship type:	protein modification catalytic chemical reaction protein-protein interaction compound-protein interaction TF-target gene regulation small RNA-target regulation co-expressed gene pair carrier and transported molecule family/complex and member
Relationship evidence:	Solid line: validated Dashed line: predicted
Relationship direction:	Arrow: positive T shape: negative None arrow: unknown or n/a
Hormone association:	Thicker line: hormone related relationship : hormone related Node
Node type:	Transcription factor or transcriptional regulator Compound Kinase Small regulatory RNA (miRNA & ta-siRNA) Other nodes

No.	Path
2	AHK3 -- interacts with -- AT5G43560
3	AHK3 -- has similar expression pattern (mutual information value=0.800174) with -- AT2G35680
4	AHK3 -- has similar expression pattern (mutual information value=0.887826) with -- AT1G21780
5	AHK3 -- is a member of -- AHK3 family64, response regulator and putative novel transcription factor gene
6	AHK3 -- is a member of -- AHK4 family65, response regulator and putative novel transcription factor gene
7	AHK3 -- interacts with -- AT5G43560 -- has similar expression pattern (mutual information value=0.855543) with -- AT5G41940
8	AHK3 -- interacts with -- AT5G43560 -- interacts with -- AT-HSFB2B; HSFB2B
9	AHK3 -- has similar expression pattern (mutual information value=0.887826) with -- AT1G21780 -- interacts with -- ATCUL3B; CUL3B
10	AHK3 -- has similar expression pattern (mutual information value=0.887826) with -- AT1G21780 -- interacts with -- ATCUL3; ATCUL3A; CUL3; CUL3A
11	AHK3 -- is a member of -- AHK3 family64, response regulator and putative novel transcription factor gene -- has family member -- AHK2
12	AHK3 -- is a member of -- AHK3 family64, response regulator and putative novel transcription factor gene -- has family member -- AHK4
13	AHK3 -- is a member of -- AHK4 family65, response regulator and putative novel transcription factor gene -- is a member of -- zeatin complex17

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