Welcome to HRGRN: A Graph Search-Empowered Integrative Database of Arabidopsis Signaling Transduction, Metabolism and Gene Regulation Networks

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	Welcome to HRGRN A Graph Search-Empowered Integrative Database of Arabidopsis Signaling Transduction, Metabolism and Gene Regulation Networks

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Relationship Details

Type: protein-protein interaction	GRN ID: re266547	Name: protein-protein interaction	Validated: Y
Direction:	Negative
Steps:	Direct effect
Upstream node(s):	ARAC4; ATRAC4; ATROP2; ROP2 RIC4
Downstream node(s):	ATPIN1
Pathways:	Auxins
References:	Nagawa S, Xu T, Lin D, Dhonukshe P, Zhang X, Friml J, Scheres B, Fu Y, Yang Z. ROP GTPase-dependent actin microfilaments promote PIN1 polarization by localized inhibition of clathrin-dependent endocytosis. PLoS Biol. 2012;10(4):e1001299. doi: 10.1371/journal.pbio.1001299. Epub 2012 Apr 3. PubMed PMID: 22509133; PubMed Central PMCID: PMC3317906.

	Funding by the National Science Foundation		Funding by the Oklahoma Center for the Advancement of Science & Technology		Additional funding by the Samuel Roberts Noble Foundation

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