Welcome to HRGRN: A Graph Search-Empowered Integrative Database of Arabidopsis Signaling Transduction, Metabolism and Gene Regulation Networks

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	Welcome to HRGRN A Graph Search-Empowered Integrative Database of Arabidopsis Signaling Transduction, Metabolism and Gene Regulation Networks

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Relationship Details

Type: TF-target gene regulation	GRN ID: re266176	Name: TF-target gene regulation	Validated: Y
Direction:	Negative
Steps:	Direct effect
Upstream node(s):	ETO family, chromatin remodeling & transcription regulator gene
Downstream node(s):	ATCUL3; ATCUL3A; CUL3; CUL3A
Pathways:	Ethylene
References:	Christians MJ, Gingerich DJ, Hansen M, Binder BM, Kieber JJ, Vierstra RD. The BTB ubiquitin ligases ETO1, EOL1 and EOL2 act collectively to regulate ethylene biosynthesis in Arabidopsis by controlling type-2 ACC synthase levels. Plant J. 2009 Jan;57(2):332-45. doi: 10.1111/j.1365-313X.2008.03693.x. Epub 2008 Oct 30. PubMed PMID: 18808454; PubMed Central PMCID: PMC2807402.

	Funding by the National Science Foundation		Funding by the Oklahoma Center for the Advancement of Science & Technology		Additional funding by the Samuel Roberts Noble Foundation

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