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Relationship Details
Type: protein-protein interaction GRN ID: re144995 Name: Validated: Y
Direction: Unknown or N/A
Steps: Direct effect
Upstream node(s):
Downstream node(s):
Pathways: Jasmonates;  Salicylic acid
References:
  • Zhou JM, Trifa Y, Silva H, Pontier D, Lam E, Shah J, Klessig DF. NPR1 differentially interacts with members of the TGA/OBF family of transcription factors that bind an element of the PR-1 gene required for induction by salicylic acid. Mol Plant Microbe Interact. 2000 Feb;13(2):191-202. PubMed PMID: 10659709.
  • Kim HS, Delaney TP. Over-expression of TGA5, which encodes a bZIP transcription factor that interacts with NIM1/NPR1, confers SAR-independent resistance in Arabidopsis thaliana to Peronospora parasitica. Plant J. 2002 Oct;32(2):151-63. PubMed PMID: 12383081.
  • Després C, Chubak C, Rochon A, Clark R, Bethune T, Desveaux D, Fobert PR. The Arabidopsis NPR1 disease resistance protein is a novel cofactor that confers redox regulation of DNA binding activity to the basic domain/leucine zipper transcription factor TGA1. Plant Cell. 2003 Sep;15(9):2181-91. PubMed PMID: 12953119; PubMed Central PMCID: PMC181339.
  • Zhang Y, Fan W, Kinkema M, Li X, Dong X. Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6523-8. PubMed PMID: 10339621; PubMed Central PMCID: PMC26915.
  • Després C, DeLong C, Glaze S, Liu E, Fobert PR. The Arabidopsis NPR1/NIM1 protein enhances the DNA binding activity of a subgroup of the TGA family of bZIP transcription factors. Plant Cell. 2000 Feb;12(2):279-90. PubMed PMID: 10662863; PubMed Central PMCID: PMC139764.
  • Liu G, Holub EB, Alonso JM, Ecker JR, Fobert PR. An Arabidopsis NPR1-like gene, NPR4, is required for disease resistance. Plant J. 2005 Jan;41(2):304-18. PubMed PMID: 15634206.
  • Shi Z, Maximova S, Liu Y, Verica J, Guiltinan MJ. The salicylic acid receptor NPR3 is a negative regulator of the transcriptional defense response during early flower development in Arabidopsis. Mol Plant. 2013 May;6(3):802-16. doi: 10.1093/mp/sss091. Epub 2012 Sep 17. PubMed PMID: 22986789.
  • Kesarwani M, Yoo J, Dong X. Genetic interactions of TGA transcription factors in the regulation of pathogenesis-related genes and disease resistance in Arabidopsis. Plant Physiol. 2007 May;144(1):336-46. Epub 2007 Mar 16. PubMed PMID: 17369431; PubMed Central PMCID: PMC1913812.
 
Cross Reference: biogrid:269005  biogrid:269024  biogrid:331630  biogrid:334162  biogrid:334163  biogrid:334600  biogrid:334602  biogrid:336023  biogrid:723027  
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