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Location:  Home > Details for node COS1
Type: Protein GRN ID: np07032 Name: COS1
Annotation: COS1 | 6,7-dimethyl-8-ribityllumazine synthase / DMRL synthase / lumazine synthase / riboflavin synthase [EC:2.5.1.78]
Gene Locus: AT2G44050
References:
  • Xiao S, Dai L, Liu F, Wang Z, Peng W, Xie D. COS1: an Arabidopsis coronatine insensitive1 suppressor essential for regulation of jasmonate-mediated plant defense and senescence. Plant Cell. 2004 May;16(5):1132-42. Epub 2004 Apr 9. PubMed PMID: 15075400; PubMed Central PMCID: PMC423205.
 
Pathways: Jasmonates 
Gene Expression (Affy ATH1 probeset): 267188_at    
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 Protein modification
 Protein-protein interaction
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 Compound-protein interaction
 TF-target gene regulation
 Small RNA-target regulation
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 Catalytic chemical reaction
 Co-expressed gene pair
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Relationship type:  protein modification     catalytic chemical reaction     protein-protein interaction    
compound-protein interaction     TF-target gene regulation     small RNA-target regulation    
co-expressed gene pair     carrier and transported molecule     family/complex and member
Relationship evidence:  Solid line: validated          Dashed line: predicted
Relationship direction: Arrow: positive          T shape: negative          None arrow: unknown or n/a
Hormone association: Thicker line: hormone related relationship         : hormone related Node
Node type:  Transcription factor or transcriptional regulator       Compound       Kinase
 Small regulatory RNA (miRNA & ta-siRNA)       Other nodes
No. Path
2 COS1  --  has product (in catalytic reaction)  --  6,7-Dimethyl-8-(D-ribityl)lumazine
3 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1
4 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090
5 COS1  --  has similar expression pattern (mutual information value=0.814764) with  --  AT1G14810
6 COS1  --  has similar expression pattern (mutual information value=0.962132) with  --  MAR1; TOC75-III
7 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2
8 COS1  --  has product (in catalytic reaction)  --  6,7-Dimethyl-8-(D-ribityl)lumazine  --  is product (in catalytic reaction) of  --  5-Amino-6-(1-D-ribitylamino)uracil
9 COS1  --  has product (in catalytic reaction)  --  6,7-Dimethyl-8-(D-ribityl)lumazine  --  is product (in catalytic reaction) of  --  L-3,4-Dihydroxybutan-2-one 4-phosphate
10 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ATCBL2; CBL2
11 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  CBL9
12 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ATCBL3; CBL3
13 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  CIR1; RVE2
14 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT2G39050
15 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  anac032; NAC032
16 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT1G10585
17 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT2G01690
18 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT5G11200
19 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT1G28060
20 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ATNRP1; NRP1
21 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT2G22360
22 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT5G67385
23 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  SEC61 BETA
24 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AtMYB49; MYB49
25 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  SSP4
26 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT5G43520
27 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  RGL3
28 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ABI1
29 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT4G16670
30 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AtMYB74; MYB74
31 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ATHB-12; ATHB12; HB-12
32 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ATFER3; FER3
33 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ATWNK2; WNK2; ZIK3
34 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ANAC055; ATNAC3; NAC055; NAC3
35 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  RAP2.2
36 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ATMYB12; MYB12; PFG1
37 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AtCLO3; CLO-3; CLO3; RD20
38 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  CIPK11; PKS5; SIP4; SNRK3.22
39 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ATHB6
40 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ATCOR413-PM1; ATCYP19; COR413-PM1; FL3-5A3; WCOR413; WCOR413-LIKE
41 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT1G73920
42 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ANAC019; NAC019
43 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  ANAC018; ATNAM; NAM; NARS2
44 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  RAP2.4
45 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  PKP-ALPHA; PKP1
46 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT2G19650
47 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  IAA11
48 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT2G46550
49 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  AT1G01240
50 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  CBL8
51 COS1  --  interacts with  --  ATCIPK14; ATSR1; CIPK14; PKS24; SnRK3.15; SR1  --  interacts with  --  CBL6; SCABP2
52 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090  --  has similar expression pattern (mutual information value=0.861802) with  --  OMR1
53 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090  --  has similar expression pattern (mutual information value=0.864618) with  --  ATGRP2; GR-RBP2; GRP2
54 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090  --  has similar expression pattern (mutual information value=1.11505) with  --  AT3G62460
55 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090  --  has similar expression pattern (mutual information value=1.11505) with  --  AT3G62530
56 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090  --  has similar expression pattern (mutual information value=0.820888) with  --  AT5G37310
57 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090  --  has similar expression pattern (mutual information value=1.14828) with  --  AT5G17630
58 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090  --  has product (in catalytic reaction)  --  2-Methylmaleate
59 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090  --  has product (in catalytic reaction)  --  2-Isopropylmaleate
60 COS1  --  has similar expression pattern (mutual information value=1.22346) with  --  AT2G43090  --  has product (in catalytic reaction)  --  alpha-Isopropylmalate
61 COS1  --  has similar expression pattern (mutual information value=0.814764) with  --  AT1G14810  --  has similar expression pattern (mutual information value=0.846337) with  --  RACK1B; RACK1B_AT
62 COS1  --  has similar expression pattern (mutual information value=0.814764) with  --  AT1G14810  --  has similar expression pattern (mutual information value=0.875554) with  --  ATHDH; HDH; HISN8
63 COS1  --  has similar expression pattern (mutual information value=0.814764) with  --  AT1G14810  --  has similar expression pattern (mutual information value=0.937021) with  --  ATCPN21; CHCPN10; CPN10; CPN20; CPN21
64 COS1  --  has similar expression pattern (mutual information value=0.814764) with  --  AT1G14810  --  has product (in catalytic reaction)  --  4-Phospho-L-aspartate
65 COS1  --  has similar expression pattern (mutual information value=0.962132) with  --  MAR1; TOC75-III  --  has similar expression pattern (mutual information value=0.856739) with  --  PDE328; SVR1
66 COS1  --  has similar expression pattern (mutual information value=0.962132) with  --  MAR1; TOC75-III  --  has similar expression pattern (mutual information value=0.843164) with  --  AtHsp90.5; CR88; EMB1956; Hsp88.1; HSP90.5
67 COS1  --  has similar expression pattern (mutual information value=0.962132) with  --  MAR1; TOC75-III  --  has similar expression pattern (mutual information value=0.812478) with  --  RH39
68 COS1  --  has similar expression pattern (mutual information value=0.962132) with  --  MAR1; TOC75-III  --  interacts with  --  AFT; AKR2; AKR2A
69 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  interacts with  --  ATHSP23.6-MITO; HSP23.6-MITO
70 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  interacts with  --  AHK2
71 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.86418) with  --  ATMEPCT; ISPD; MCT
72 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.879141) with  --  CHL-CPN10; CPN10
73 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.856223) with  --  ATCDPMEK; CDPMEK; ISPE; PDE277
74 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=1.13063) with  --  AT2G19940
75 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.900342) with  --  AT2G42770
76 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.901969) with  --  ABCI7; ATNAP6; NAP6
77 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.858908) with  --  ACS1; ATCS-B; CPACS1; OASB
78 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.822562) with  --  AT4G32440
79 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.962284) with  --  PYRR; UPP
80 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.988248) with  --  AtPPa6; PPa6
81 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has similar expression pattern (mutual information value=0.845995) with  --  PCB2
82 COS1  --  has similar expression pattern (mutual information value=0.801444) with  --  ATCYP20-2; CYP20-2  --  has product (in catalytic reaction)  --  Peptidylproline (omega=0)
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