| Location: Details of ZF-HD family |
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ZF-HD |
| Family Type |
Transcription factor |
| Plant Specific |
No |
| Functional Domains |
DNA binding domain |
| Must-have InterProScan Domain Pattern |
IPR006456 or IPR006455 |
| Prohibited InterProScan Domain Pattern |
IPR007087 |
| Description |
Homeobox genes encode a typical DNA-binding domain of 60 amino acids, known as homeodomain. Typically, homeodomain folds into characteristic 3D structure containing three alpha-helices, of which the second and third form a helix-turn-helix motif. ZF-HD group of Zn finger proteins have two highly conserved zinc finger?Clike motifs upstream of the homeodomain. The first putative zinc finger has a consensus sequence C-X3-H-X9-D-X1-C, where H is not always conserved, and the second putative zinc finger has the following pattern C-X2-C-X1-C-H-X3-H.
Reference:
1. K. Mukherjee, L. Brocchieri, T. R. Burglin, A comprehensive classification and evolutionary analysis of plant homeobox genes. Mol Biol Evol 26, 2775 (2009).
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| Cross-reference to other databases |
The family is the same family of ZF-HD in PlantTFDB.
The family is the same family of zf-HD in PlnTFDB.
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