Location: Details of WRKY family |
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WRKY |
Family Type |
Transcription factor |
Plant Specific |
Yes |
Functional Domains |
DNA binding domain |
Must-have InterProScan Domain Pattern |
IPR003657 or IPR017396 or IPR017412 |
Prohibited InterProScan Domain Pattern |
IPR004330 |
Description |
This is a plant specific transcription factor family. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4?C5Cx22?C23HxH or Cx7Cx23HxC. The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).
Reference:
1. P. J. Rushton, I. E. Somssich, P. Ringler, Q. J. Shen, WRKY transcription factors. Trends Plant Sci 15, 247 (2010).
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Cross-reference to other databases |
The family is the same family of WRKY in PlantTFDB.
The family is the same family of WRKY in PlnTFDB.
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