All members of the SHI/STY protein family possess two conserved regions that encode a zinc-finger domain and the unique IGGH domain. SHI/STY is a plant specific transcription factor family. This protein has a zinc binding RING finger motif type domain. The putative RING domains is composed of 31 amino acid residues in a Cys-X2-Cys-X7-Cys-X-His-X2-Cys-X2-Cys-X7-Cys-X2-His consensus arrangement (X denotes any amino acid). The second conserved region of the SHI family proteins is positioned in the C-terminal part. This domain is unique to proteins in the SHI family and does not show similarity to any previously described protein motif. This second conserved region will be referred to as the IGGH domain, named after four highly conserved residues within the region. A short acidic cluster is present in the IGGH domain in several of the SHI-related proteins.

Reference:

1. I. Fridborg, S. Kuusk, M. Robertson, E. Sundberg, The Arabidopsis protein SHI represses gibberellin responses in Arabidopsis and barley. Plant Physiol 127, 937 (2001).

2. D. L. Smith, N. V. Fedoroff, LRP1, a gene expressed in lateral and adventitious root primordia of arabidopsis. Plant Cell 7, 735 (1995)

The family is the synonymous family of SRS in PlantTFDB.

The family is the superfamily family of SRS in PlnTFDB.