| Location: Details of SSXT family |
| |
SSXT |
| Family Type |
Putative novel transcription factor |
| Plant Specific |
No |
| Functional Domains |
Protein-protein interacting domain |
| Must-have InterProScan Domain Pattern |
IPR007726 |
| Prohibited InterProScan Domain Pattern |
- |
| Description |
This protein was first described in synovial sarcomas carcinoma. By the fusion of SYT and the SSX proteins this new transcriptional regulator is generated. The SYT-SSX chimeric proteins are likely to be involved in the transcriptional deregulation of specific target genes. The genes normally regulated by SYT or SSX proteins through putative direct or indirect protein-protein interactions with specific transcription. This protein is predicted as a transcriptional repressor.
Reference:
1. M. Ladanyi, Fusions of the SYT and SSX genes in synovial sarcoma. Oncogene 20, 5755 (2001). |
| Cross-reference to other databases |
The family is only defined in PlantTFcat.
|