| Location: Details of Homeodomain-PHD family |
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Homeodomain-PHD |
| Family Type |
Chromatin remodeling & transcription regulator |
| Plant Specific |
No |
| Functional Domains |
DNA binding domain |
| Must-have InterProScan Domain Pattern |
(IPR001356 or IPR009057) and (IPR001965 or IPR011011 or IPR019787 or IPR019786) |
| Prohibited InterProScan Domain Pattern |
IPR001005 IPR006447 IPR006712 IPR006456 IPR004022 IPR018501 IPR018500 |
| Description |
Plant homeobox genes can be classified into 14 classes based on sequence differentiation and fusion with characteristic codomain sequences. Homeobox genes encode a typical DNA-binding domain of 60 amino acids, known as homeodomain. Typically, homeodomain folds into characteristic 3D structure containing three alpha-helices, of which the second and third form a helix-turn-helix motif. In some of the HB protein along with the HB domain it also contain PHD codomain. PHD domain are usually located several hundred amino acids upstream of the homeodomain.
Reference:
1. Mukherjee, K., Brocchieri, L., and Burglin, T.R. (2009). A comprehensive classification and evolutionary analysis of plant homeobox genes. Mol Biol Evol 26, 2775-2794.
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| Cross-reference to other databases |
The family is the synonymous family of HB-PHD in PlantTFDB.
The family is the subfamily family of PHD in PlnTFDB.
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