| Location: Details of Hap2/NF-YA family |
| |
Hap2/NF-YA |
| Family Type |
Transcription factor |
| Plant Specific |
No |
| Functional Domains |
DNA binding domain/Protein-Protein interacting domain |
| Must-have InterProScan Domain Pattern |
IPR001289 or IPR018362 |
| Prohibited InterProScan Domain Pattern |
- |
| Description |
In most species, Nuclear Factor Y (NF-Y) transcription factors are present. They usually composed three subunits: NF-YA/HAP2, NF-YB/HAP3, and NF-YC/HAP5. This group of TF has been implicated in diverse developmental process from animal to plant.
Plant genes belonging to the NF-YA family encode putative TFs. NF-YA??s DNA binding domain, shares some homology with the CCT domain of the nuclear flowering time regulator CONSTANS (CO). NF-YA proteins are characterized by two domains one is a (A1) of 20 amino acids forming a putative alpha helix that appears to be crucial for the interaction with NF-YB and NF-YC. A second adjacent domain (A2) of 21 amino acids, separated from A1 by a conserved linker sequence, was shown to be required for specific DNA binding to CCAAT boxes.
Reference:
1. T. Laloum, S. De Mita, P. Gamas, M. Baudin, A. Niebel, CCAAT-box binding transcription factors in plants: Y so many? Trends Plant Sci, (2012).
|
| Cross-reference to other databases |
The family is the synonymous family of NF-YA in PlantTFDB.
The family is the subfamily family of CCAAT in PlnTFDB.
|