Location: Details of HSF-type-DNA-binding family |
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HSF-type-DNA-binding |
Family Type |
Transcription factor |
Plant Specific |
No |
Functional Domains |
DNA binding domain |
Must-have InterProScan Domain Pattern |
IPR000232 or IPR010542 |
Prohibited InterProScan Domain Pattern |
- |
Description |
Heat shock factors were shown to be involved in binding to the heat shock response elements (HSE) in heat shock promoters and activating transcription. . Members of the hsf family share structural domains and functional properties including a highly conserved N-terminal DNA binding domain and a heptad repeat ??leucine zipper?? structure adjacent to the DNA binding domain that regulates trimerization and the ability to bind DNA. 1. C. Wu, Activating protein factor binds in vitro to upstream control sequences in heat shock gene chromatin.
Reference:
1. Nature 311, 81 (1984) 2. H. He, F. Soncin, N. Grammatikakis, Y. Li, A. Siganou, J. Gong, S. A. Brown, R. E. Kingston, S. K. Calderwood, Elevated expression of heat shock factor (HSF) 2A stimulates HSF1-induced transcription during stress. J Biol Chem 278, 35465 (2003) |
Cross-reference to other databases |
The family is the synonymous family of HSF in PlantTFDB.
The family is the synonymous family of HSF in PlnTFDB.
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