Location: Details of HD-ZIP family |
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HD-ZIP |
Family Type |
Transcription factor |
Plant Specific |
No |
Functional Domains |
DNA binding domain |
Must-have InterProScan Domain Pattern |
IPR006712 or IPR006456 |
Prohibited InterProScan Domain Pattern |
IPR001965 IPR011011 IPR019787 IPR019786 IPR001005 IPR005541 IPR005540 IPR008422 IPR006563 IPR004022 IPR018501 IPR018500 |
Description |
Homeobox genes encode a typical DNA-binding domain of 60 amino acids, known as homeodomain. Typically, homeodomain folds into characteristic 3D structure containing three alpha-helices, of which the second and third form a helix-turn-helix motif. The HD-ZIP superclass is characterized by presence of a leucine-zipper adjacent to the C-terminus of the homeodomain. This super class is further subdivided into four individual classes, HD-ZIP I, HD-ZIP II, HD-ZIP III, and HD-ZIP IV.
Reference:
1. K. Mukherjee, T. R. Burglin, Comprehensive analysis of animal TALE homeobox genes: new conserved motifs and cases of accelerated evolution. J Mol Evol 65, 137 (2007). |
Cross-reference to other databases |
The family is the same family of HD-ZIP in PlantTFDB.
The family is the superfamily family of zf-HD HB in PlnTFDB.
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