| Location: Details of CW-Zn family |
| |
CW-Zn |
| Family Type |
Putative transcription factor & chromatin remodeling |
| Plant Specific |
No |
| Functional Domains |
DNA binding domain and Protein Protein Interaction |
| Must-have InterProScan Domain Pattern |
IPR011124 |
| Prohibited InterProScan Domain Pattern |
IPR003340 IPR001965 |
| Description |
CW-type zinc finger motif, named for its conserved cysteine and tryptophan residues. In human it has been shown to be is required for histon demethylase activity.
Reference:
1. Q. Zhang, S. Qi, M. Xu, L. Yu, Y. Tao, Z. Deng, W. Wu, J. Li, Z. Chen, J. Wong, Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b. Cell Res 23, 225 (2013) |
| Cross-reference to other databases |
The family is only defined in PlantTFcat.
|