Description |
CCCH zinc finger proteins are characterized by three cysteine residues and one histidine residue that coordinate the zinc ion and form, a CCCH-type zinc finger. In plant the most abundant type of CCCH finger is C-X8-C-X5-C-X3-H followed by C-X7-C-X5-C-X3-H other rare type of Zn-finger are also available in plant such as C-X7-C-X4-C-X3-H, C-X5-C-X4-C-X3-H, C-X7-CX6-C-X3-H etc. Although the majority of the CCCH motifs bind RNA, DNA binding CCCH-type zinc finger proteins have also been confirmed. Arabidopsis PEI encodes a protein containing a C3H zinc finger domain.
Reference:
1. X. Peng, Y. Zhao, J. Cao, W. Zhang, H. Jiang, X. Li, Q. Ma, S. Zhu, B. Cheng, CCCH-type zinc finger family in maize: genome-wide identification, classification and expression profiling under abscisic acid and drought treatments. PLoS One 7, e40120 (2012).
2. Z. Li, T. L. Thomas, PEI1, an embryo-specific zinc finger protein gene required for heart-stage embryo formation in Arabidopsis. Plant Cell 10, 383 (1998).
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