| Location: Details of BTB-POZ family |
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BTB-POZ |
| Family Type |
Chromatin remodeling & transcription regulator |
| Plant Specific |
No |
| Functional Domains |
Protein-protein interacting domain |
| Must-have InterProScan Domain Pattern |
IPR000210 or IPR011333 |
| Prohibited InterProScan Domain Pattern |
IPR002110 IPR002083 IPR016072 IPR001232 IPR004249 |
| Description |
The BTB/POZ domain is an evolutionarily conserved protein-protein interaction domain that is found at the N terminus of some C2H2-type zinc finger transcription factors and in actin binding proteins. Examples of the BTB/POZ domain have been identified in organisms from yeast to human. The BTB (for Broad Complex, tramtrack and bric a brac) / POZ (for poxviruses and zinc finger) is an approximately 20-amino acid conserved and hydrophobic domain present generally at the NH2-terminal end of numerous proteins. BTB/POZ-containing protein which was originally regarded as a classical positive transcription factor recently also have been implicated in large scale chromatin modeling, by creating and/or maintaining chromatin structure.
Reference:
1. Albagli, O., Dhordain, P., Deweindt, C., Lecocq, G., and Leprince, D. (1995). The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins.
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| Cross-reference to other databases |
The family is only defined in PlantTFcat.
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