| Location: Details of BES/BZR family |
| |
BES/BZR |
| Family Type |
Transcription factor |
| Plant Specific |
Yes |
| Functional Domains |
DNA binding domain |
| Must-have InterProScan Domain Pattern |
IPR008540 |
| Prohibited InterProScan Domain Pattern |
- |
| Description |
BZR and BES are brasinosteroid regulated transcription factors. This is a plant specific group of TF. In BZR1 and BES1 have a high sequence similarity (88% sequence identity at the protein level). But still they proposed to have different mode of action. BZR1 binds to the CGTG(T/C)G motif (also known as BR-Response Element or BRRE) to suppress gene expression of BR-biosynthetic genes . On the other hand BES1 binds the CANNTG sequence (also known as E box) to activate BR-induced gene expression.
Reference:
1. G. E. Gudesblat, E. Russinova, Plants grow on brassinosteroids. Curr Opin Plant Biol 14, 530 (2011) 2. J. X. He, J. M. Gendron, Y. Sun, S. S. Gampala, N. Gendron, C. Q. Sun, Z. Y. Wang, BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses. Science 307, 1634 (2005) |
| Cross-reference to other databases |
The family is the synonymous family of BES1 in PlantTFDB.
The family is the synonymous family of BES1 in PlnTFDB.
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